PLATFORM

Blood-based profiling of the tumor microenvironment.

Clyra combines complementary molecular layers from routine blood draws into a repeatable view of tumor microenvironment composition and activity during treatment.

REPEATABLE TME PROFILING

01

At baseline

Characterize the tumor microenvironment before treatment.

Characterize the tumor microenvironment before treatment.

02

During treatment

Track changes in composition and activity over time.

Track changes in composition and activity over time.

One tissue snapshot is not enough.

Immunotherapies and other TME-dependent drugs are often selected and evaluated on a single biopsy taken before treatment. The tumor microenvironment changes over time and under therapy, and repeat biopsies are invasive and rarely feasible. Development teams are left making decisions on a static, partial view.

A static view of a changing system

PLATFORM

One blood draw. A view of the tumor microenvironment.

01

Routine blood draw

A standard blood sample, collected at any visit.

02

Complementary molecular layers

Multiple molecular layers capture both the cellular composition of the tumor microenvironment and what those cells are doing.

03

Integrated TME state

The layers are combined into a single TME readout that no single layer provides alone, and it can be repeated at every visit.

WHY CLYRA

What makes Clyra different.

Composition and activity

We read which cells are present and what they are doing, not just one or the other.

Longitudinal by design

Blood-based, so the tumor microenvironment can be measured repeatedly over the course of treatment.

Built with drug developers

Deliverables designed around trial decisions: patient selection, biomarker strategy, and next-phase design.

DISCUSS A PROGRAM

What decision does your program need to make?

If you are selecting patients for a TME-dependent therapy, building a biomarker strategy, or interpreting early clinical data, let’s discuss your program.

DISCUSS A PROGRAM

What decision does your program need to make?

If you are selecting patients for a TME-dependent therapy, building a biomarker strategy, or interpreting early clinical data, let’s discuss your program.

DISCUSS A PROGRAM

What decision does your program need to make?

If you are selecting patients for a TME-dependent therapy, building a biomarker strategy, or interpreting early clinical data, let’s discuss your program.

CLYRA BIO

Clyra is building blood-based tumor microenvironment profiling for oncology drug development.

Clyra analyses are intended to support research and drug-development decisions. Candidate biomarkers require appropriate independent and clinical validation.

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